Purpose

To determine the oncologic benefit or otherwise of local treatment of the prostate in patients with primary metastatic prostate cancer.

Methods

A review of the literature was performed in April 2014 using the Medline/PubMed database. Studies were identified using the search terms “prostate cancer,” “metastatic,” “metastasis,” “high risk,” “radiation therapy,” “radiotherapy” and “prostatectomy” from 1990 until April, 2014. Articles were also identified through searches of references of these articles.

Results

Retrospective series and population-based data suggest that the use of local treatment of the prostate in patients with primary metastatic prostate cancer may improve cancer-specific survival and overall survival compared with treating these patients with androgen deprivation therapy alone.

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